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Morphine-Induced Immunosuppression, From Brain to Spleen
Morphine sets off a chain of biological events that stifles the immune response.6/1/08Lori Whitten, NIDA Notes Staff WriterMorphine and other opioids suppress the immune system, the body's innate...
View ArticleMorphine Speeds AIDS Onset in Monkeys
6/1/08Dr. Anil Kumar and colleagues at the Ponce School of Medicine, Puerto Rico, have discovered key ways in which morphine may accelerate the progression of AIDS: The drug increases both viral...
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Endorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats
Recent studies suggest therapeutic potential for glycyl-glutamine in opiate and nicotine addiction.10/1/07Sarah Teagle, NIDA Notes Contributing WriterA naturally occurring brain chemical has shown...
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Neuropeptide Promotes Drug-Seeking and Craving in Rats
Orexin emerges as a link in the chain of brain mechanisms regulating appetite for rewards.10/1/07Lori Whitten, NIDA Notes Staff WriterOrexin, a neuropeptide that stimulates eating and regulates...
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Exposure to Morphine During Early Adolescence Sensitizes Rats as Adults
10/1/07A study conducted at Emory University School of Medicine indicates that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood. Drs. Stephen Holtzman and...
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Antipsychotic Drug Prevents Morphine Tolerance in Mice
4/1/07Dr. Zaijie Jim Wang and colleagues at the University of Illinois suppressed morphine tolerance and dependence in mice by blocking calcium/calmodulin-dependent protein kinase II (CaMKII), which...
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Program Helps Troubled Boys Reduce Substance Abuse
12/19/11Fostering Self Control: Youth in Multidimensional Treatment Foster Care live with foster parents who help them develop control over their behavior. Foster parents implement a system in which...
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Potential Pain Medication Targets Peripheral Nerves
Compound may relieve chronic pain without CNS side effects9/17/12NIDA Notes StaffOxycodone, hydrocodone, morphine, and other opioids are the most effective analgesic medications currently available,...
View ArticleMorphine-Induced Immunosuppression, From Brain to Spleen
Reports on scientists who pinpointed the biochemical trigger from morphine that sets off a chain reaction that inhibits an immune cell that is key in fighting viruses and cancer.
View ArticleMorphine Speeds AIDS Onset in Monkeys
Highlights the work of investigators who discovered key ways in which morphine may accelerate the progression of AIDS in animal studies.
View ArticleEndorphin Derivative Inhibits Reward From Morphine and Nicotine in Rats
Describes research investigating a naturally occurring brain chemical that shows early promise as a treatment for addiction in animal studies.
View ArticleNeuropeptide Promotes Drug-Seeking and Craving in Rats
Reports on two studies indicating that orexin, a neuropeptide that stimulates eating and regulates wakefulness, also fosters animals' drug seeking and craving responses to drugs.
View ArticleExposure to Morphine During Early Adolescence Sensitizes Rats as Adults
Presents highlights of a study indicating that exposure to morphine during adolescence may increase sensitivity to the drug during adulthood.
View ArticleAntipsychotic Drug Prevents Morphine Tolerance in Mice
Summarizes animal studies indicating that an antipsychotic drug, trifluoperazine, prevents morphine tolerance in mice.
View ArticleProgram Helps Troubled Boys Reduce Substance Abuse
Chronically delinquent boys in Multidimensional Treatment Foster Care reduced their substance abuse more than boys assigned to Community Group Care.
View ArticlePotential Pain Medication Targets Peripheral Nerves
Researchers report a significant advance in the search for medications that can suppress pain but avoid opioids’ abuse potential and other undesirable CNS effects. A new compound reduces mouse...
View ArticlePromising Advances in the Search for Safer Opioids
New studies show that two novel compounds powerfully suppressed animals’ pain responses, while producing little or none of the respiratory depression and liability for misuse and abuse associated with...
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Medications to Treat Opioid Use Disorder
Discusses effective medications used to treat opioid use disorders: methadone, buprenorphine, and naltrexone. mayo del 2017junio del 2018 National Institute on Drug Abuse Serie de reportes de...
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Opioid Facts for Teens
Presented in question-and-answer format and targeted to teens, provides facts about opioids and their potential harmful effects. 18-DA-8054julio del 2018julio del 2018 National Institute on Drug...
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Los opioides: Información para adolescentes
18-DA-8054julio del 2018National Institute on Drug Abuse Drug Overdoses in YouthFentanylHeroínaOpioidesMedicamentos sin necesidad de prescripciónMedicamentos de...
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